General references
Below are references to briefly introduce the general history of mycovirus discovery and the viruses, parasites, and toxins of S. cerevisiae
A general review of mycoviruses
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A description of the major viruses and molecular parasites that are harbored by S. cerevisiae and thoughts on the potential genetic conflict between the host and resident viruses.
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A general review of the major killer toxins that are produced by Saccharomyces yeasts
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Wickner, R. B., Fujimura, T. & Esteban, R. Viruses and prions of S. cerevisiae. Adv Virus Res 86, 1–36 (2013).
A description of the major viruses, molecular parasites, and prions that are harbored by S. cerevisiae
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MYCOVIRUS DISCOVERY
The description of La France disease and the discovery that fragments of intact mycelium from Agaricus bisporus are sufficient to transmit disease. This provides evidence that mycoviruses are not transmitted in the environment but by anastomosis.
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Injection of mycelial extracts provides a protective effect to laboratory animals challenged with lethal viruses. The agent was named "Helenine" but is not specifically identified (see Banks et al. below)
Banks, G. T. et al. Viruses in Fungi and Interferon Stimulation. Nature 218, 542–545 (1968).
Analysis of antiviral fungal extract named "Helenine" and "Statolon" to confirm that antiviral interferon induction is caused by mycoviruses with double-stranded RNA genomes.
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TOTIVIRUSES AND DOUBLE-STRANDED RNAs OF YEASTS
The discovery of double-stranded RNA in killer yeasts - corresponding to totiviruses and satellites within killer yeasts.
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The description of virus-like particles that are associated with S. cerevisiae
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The first description of killer yeast.
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Confirmation that killer toxin production is inherited from the cytoplasm and the nuclear genome.
The polymerase of the L-A totivirus is required for packaging viral transcripts
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KILLER YEASTS
The first description of killer yeast.
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Confirmation that killer toxin production is inherited from the cytoplasm and the nuclear genome.
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